Olmesartan Medoxomil & Chlorthalidone Tablets

Olmesartan Medoxomil & Chlorthalidone Tablets

Olmesartan Medoxomil 20, 40 & Chlorthalidone 12.5 Tablets


Olmesartan Medoxomil and Chlorthalidone Tablets belong to the class of medicines called antihypertensives primarily used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Olmesartan Medoxomil and Chlorthalidone Tablets is a combination of two medicines namely: Olmesartan Medoxomil and Chlorthalidone. Olmesartan medoxomil is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Chlorthalidone is a diuretic or water pill that removes extra water and certain electrolytes from the body. Together it lowers fluid overload, and blood pressure and improves blood flow.

Medical Benefits 

  • Olmesartan Medoxomil and Chlorthalidone Tablets are combination medications, generally used when a single medicine is not effective in controlling blood pressure. 
  • It is used to treat hypertension, where Olmesartan medoxomil works by relaxing the blood vessels. 
  • Chlorthalidone being diuretic works by increasing the amount of urine that is passed out from the kidneys and hence lowering the blood pressure. 
  • It lowers the overall raised blood pressure and reduces the risk of having a heart attack, stroke, or kidney problems.

Directions For Use 

  • It should not be used unless prescribed by a doctor. 
  • Always take this tablet exactly as your doctor told you. 
  • Your doctor will advise you how often you take your tablets on the basis of your medical condition. 
  • Swallow this medicine with a full glass of water.


  • Keep it away from sunlight.
  • Keep out of the reach of children.
  • Store in a cool and dry place. 


  • It may interact with other high blood pressure-lowering pills (benazepril, metoprolol, ramipril, hydrochlorothiazide, simvastatin, diltiazem, verapamil, azilsartan, benazepril, lisinopril, amiloride), and can lower your blood pressure leading to severe condition.
  • You are recommended not to consume alcohol along with this tablet to avoid unpleasant side effects.
  • Olmesartan Medoxomil and Chlorthalidone Tablets is a Category C/D pregnancy drug which is considered unsafe for pregnant women and can have some harmful effects on the baby (foetus).
  • This medicine is not recommended for breastfeeding mothers. It is excreted into milk in small amounts and can be accumulated in the infant.

Side Effects 

  • Bradycardia (slow heart rate)
  • Cold extremities
  • Gastrointestinal disturbances including nausea
  • Fatigue

Frequently Asked Questions (FAQs)

Can the use of this medicine cause dizziness?

Yes, it can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking this tablet. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

Can taking it cause dehydration?

Taking this medicine may cause dehydration. So, to avoid dehydration, drink plenty of fluids and inform your doctor if you feel extremely thirsty.

Can this tablet cause dizziness?

It may cause dizziness, if you are lying down or sitting get up slowly to avoid it.

Will this composition affect my fertility?

It's unlikely that this tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For the best advice, consult your doctor.

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