Metformin Hydrochloride + Glimepiride Tablets

DULCOPRO M1

DULCOPRO M2

Metformin Hydrochloride + Glimepiride Tablets

Metformin Hydrochloride + Glimepiride Tablets belongs to a class of medicines called anti-diabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin, or the insulin produced is unable to perform its function in the body (insulin resistance).

Metformin Hydrochloride + Glimepiride Tablets is a combination of two antidiabetic drugs: Glimepiride and Metformin. Glimepiride works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases muscle cells' sensitivity to insulin, enabling these cells to remove sugar more effectively from the blood.

Medical Benefits 

• Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. 
• Metformin PR is a prolonged-release formulation that releases the drug in smaller portions over a longer duration of time. 
• Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. 
• Also, it increases muscle cells' sensitivity to insulin, enabling these cells to remove sugar more effectively from the blood.

Directions For Use
 

• Take it with or without food as advised by the doctor. 
• Swallow it as a whole with a glass of water. 
• Do not break, crush or chew it. 
• Please take Metformin Hydrochloride + Glimepiride Tablets in the dose and duration prescribed by your doctor based on specific medical conditions.

Storage 

• Keep it away from sunlight.
• Keep out of the reach of children.
• Store in a cool and dry place. 

Precautions

• This tablet may have interaction with antibiotics (rifampicin, trimethoprim), calcium channel blockers (verapamil), antacids (cimetidine), HIV/AIDS drugs (dolutegravir), heart-related medicine (ranolazine), etc.
• Avoid the consumption of alcohol with this medicine as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).
• Metformin Hydrochloride + Glimepiride Tablets are not recommended for pregnant women as they may harm the unborn baby.
• Avoid breastfeeding while taking this medicine as it may be excreted in breast milk and cause adverse effects in the baby.

Side Effects 

• Stomach pain
• Nausea
• Diarrhoea
• Vomiting
• Headache

Frequently Asked Questions (FAQs)

Can I take this medicine with phenytoin?

You are not recommended to take it with phenytoin as it may reduce the effect of this medicine and increase blood sugar levels. However, please consult a doctor before using it with other medicines.

Does it cause low blood sugar levels?

This tablet may increase the risk of low blood sugar levels, especially with alcohol intake, exercise more than usual, and delay or missing snacks or meals. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

What is the difference between type 1 diabetes and type 2 diabetes?

In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed and completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.